Charlie Little, DO

Associate Professor of Surgery

Division of Emergency Medicine

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Education:

                Mesa State College, Colorado; 1976-1978; Biology

                University of Colorado, Boulder, CO; BA; 1978-1980; Biology

                University of Osteopathic Medicine and Health Sciences, Des Moines, IA;                

                DO; 1983-1987; Medicine

                Detroit Osteopathic Hospital, Highland Park, MI; Internship; 1987-1988

                Ohio State University Hospital, Columbus, OH; Residency; 1988-1991;    

                Emergency Medicine

                Ohio State University Hospital, Columbus, OH; Fellowship; 1991-1993;    

                Research                           


Research Interests and Areas of Expertise:


                Disaster Preparedness and Response

                Pandemic Influenza

                Cardiac arrest

                Hemorrhagic shock


Selected Publications:


Little CM, Parker MG, Callowich MC, Sartori JC: The ultrasonic detection of soft tissue foreign bodies. Invest Radiol 1986;21:275-277.


Little CM, Parker MG, Tarnopolsky R: The incidence of vasculature at risk during cricothyroidostomy. Ann Emerg Med 1986;15:805-807.


Little CM, Hobson JL, Brown CG: Angiotensin II effects in a swine model of cardiac arrest. Ann Emerg Med 1993;22:244-247.


Little CM, Hobson JL, Brown CG: Angiotensin II improves myocardial blood flow in cardiac arrest. Resuscitation 1993;26:203-210.


Little CM, Brown CG: Angiotensin II improves cerebral blood flow in cardiopulmonary arrest in swine. Stroke 1994;25:183-186.


Angelos MG, Griffith RF, Beckley PD, Rath DP, Little CM: Myocardial metabolic changes during reperfusion of ventricular fibrillation : A 31P-NMR study in swine. Crit Care Med 1995;23:733-739.


Rath DP, Little CM, Zhang H, Jiang Z, Abduljalil AM, Zhu H, Tong X, Brown C,

Hamlin RL, Robitaille PML: Sodium pentobarbital versus alpha-chloralose anesthesia, experimental production of substantially different slopes in the transmural CP/ATP ratios within the left ventricle of the canine myocardium. Circulation 1995;91:471-475.


Little CM, Angelos MG, Paradis NA: Compared to angiotensin II, epinephrine is associated with high myocardial blood flow following return of spontaneous circulation after cardiac arrest.  Resuscitation 2003;59:353-359

 

Little CM, Paradis NA, Heard K: Prehospital interventions to improve neurologic outcome following cardiac arrest. Semin Neurol 2006;4:380-386.

 

Little CM, Marietta MH, Peng K, Heard K, Severyn FA, Fragoso M, Paradis NA: Vasopressin Alone or with Epinephrine May Be Superior to Epinephrine in a Clinically Relevant Porcine Model of PEA Cardiac Arrest. Am J Emerg Med. 2006 Nov;24(7):810-4.